CHIR-090

CHIR-090

【产品别名】

【CAS号】 728865-23-4

【目录编号】 2H-42

【纯度】 >98%

【分子式】 C24H27N3O5

【分子量】 437.49

【简介】 CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin.

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CHIR-090 详细介绍

CHIR-090 is a potent LpxC inhibitor, displays two-step time-dependent inhibition and kills a wide range of Gram-negative pathogens as effectively as ciprofloxacin or tobramycin.
IC50 value:
Target: LpxC; Antibacterial; LpxC
The UDP-3-O-(R-3-hydroxyacyl)-N-acetylglucosamine deacetylase LpxC is an essential enzyme of lipid A biosynthesis in Gram-negative bacteria and a promising antibiotic target.

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