【产品别名】RAF-709;RAF 709

【CAS号】 1628838-42-5


【纯度】 98%

【分子式】 C₂₈H₂₉F₃N₄O₄

【分子量】 542.55

【简介】 RAF709 is a novel Raf kinase inhibitor

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RAF-709 详细介绍

RAF709 is a novel Raf kinase inhibitor , has an IC50 of 0.5 and 1.8 nM for c-Raf and b-Raf, respectively. IC50 & Target: 0.5 nM (c-Raf), 1.8 nM (b-Raf) InVitro: The invention provides compounds (e.g., RAF709) that inhibit Raf kinases, and are accordingly useful for treating certain disorders associated with excessive Raf kinase activity, including cell proliferation disorders such as cancers

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