Pexidartinib

Pexidartinib

【产品别名】PLX-3397;PLX3397;PLX 3397;

【CAS号】 1029044-16-3

【目录编号】 2H-82

【纯度】 >98%

【分子式】 C20H15ClF3N5

【分子量】 417.81

【简介】 Pexidartinib is a receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3, with potential antineoplastic activity, with IC50 of 28 and 16 nM for Fms and Kit, respectively.

联系我们 索取资料

Pexidartinib 详细介绍

Pexidartinib is a receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3, with potential antineoplastic activity, with IC50 of 28 and 16 nM for Fms and Kit, respectively.

Pexidartinib is a potent drug for treatment of cancer and used for Phase III TGCT clinical trial[1].


References


[1]. Gelhorn HL, et al. Patient-reported Symptoms of Tenosynovial Giant Cell Tumors. Clin Ther. 2016 Apr;38(4):778-93.


Back to top